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Search Results for " α7 nachr "

20

Compounds

Cat No. Product Name Synonyms Targets
T8868 4BP-TQS AChR
4BP-TQS is an allosteric agonist of α7 nAChRs.
T62317 α7 nAchR-JAK2-STAT3 agonist 1
α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM). α7 nAchR-JAK2-STAT3 agonist 1 has been shown to have a positive effect on iNOS, IL-1β...
T26646 AQW051 AQ W051,VQW-765,AQW-051 AChR
AQW051 (VQW-765) is an orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) specific activator that interacts with recombinant human α7-nAChR expression (pKD value 7.56). Alpha7-nachr is considered an attrac...
T23145 PHA 543613 Others , AChR
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.
T2422 PNU-282987 AChR
PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).
TQ0117 A-867744 AChR , Autophagy
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
T22016 A-582941 dihydrochloride A 582941 5-HT Receptor , AChR
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial
T12165 nAChR agonist 1 DUN71755 AChR
nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
T7695 PNU-282987 S enantiomer free base AChR
PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).
T17300 (-)-(S)-B-973B AChR
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
T8318 BNC210 H-Ile-Trp-OH,IW-2143 AChR
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
T23348 SEN12333 SEN 12333 AChR
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist
T7422 CCMI AVL-3288 AChR
CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.
T16563L Pozanicline hydrochloride AChR
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist...
T6950 PNU-120596 NSC 216666 AChR
PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
T23286 S 24795 Catestatin acetate(142211-96-9 free base),LNAChR AChR
S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist. S 24795 improves mnemonic function in aged mice and can be used in studies about aging-related memory disturbances.
T70277 Cynandione A Others
Cynandione A, an acetophenone derived from Cynanchum wilfordii, has anti-inflammatory activity and significantly reduces pro-inflammatory cytokine overexpression via macrophage α7 nAChR activation and subsequent IL-10 ex...
T14333 Asoxime dichloride Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate,Asoxime (dichloride),HI-6 AChR
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antig...
T28531 Facinicline hydrochloride RG3487 5-HT Receptor , AChR
Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot...
T28856 SSR180711 hydrochloride SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl AChR
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
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