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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8868 | 4BP-TQS | AChR | |
4BP-TQS is an allosteric agonist of α7 nAChRs. | |||
T62317 | α7 nAchR-JAK2-STAT3 agonist 1 | ||
α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM). α7 nAchR-JAK2-STAT3 agonist 1 has been shown to have a positive effect on iNOS, IL-1β... | |||
T26646 | AQW051 | AQ W051,VQW-765,AQW-051 | AChR |
AQW051 (VQW-765) is an orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) specific activator that interacts with recombinant human α7-nAChR expression (pKD value 7.56). Alpha7-nachr is considered an attrac... | |||
T23145 | PHA 543613 | Others , AChR | |
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia. | |||
T2422 | PNU-282987 | AChR | |
PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). | |||
TQ0117 | A-867744 | AChR , Autophagy | |
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM). | |||
T22016 | A-582941 dihydrochloride | A 582941 | 5-HT Receptor , AChR |
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial | |||
T12165 | nAChR agonist 1 | DUN71755 | AChR |
nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator. | |||
T7695 | PNU-282987 S enantiomer free base | AChR | |
PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR). | |||
T17300 | (-)-(S)-B-973B | AChR | |
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR. | |||
T8318 | BNC210 | H-Ile-Trp-OH,IW-2143 | AChR |
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression. | |||
T23348 | SEN12333 | SEN 12333 | AChR |
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist | |||
T7422 | CCMI | AVL-3288 | AChR |
CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric. | |||
T16563L | Pozanicline hydrochloride | AChR | |
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an α4β2-selective nAChR agonist... | |||
T6950 | PNU-120596 | NSC 216666 | AChR |
PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM. | |||
T23286 | S 24795 | Catestatin acetate(142211-96-9 free base),LNAChR | AChR |
S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist. S 24795 improves mnemonic function in aged mice and can be used in studies about aging-related memory disturbances. | |||
T70277 | Cynandione A | Others | |
Cynandione A, an acetophenone derived from Cynanchum wilfordii, has anti-inflammatory activity and significantly reduces pro-inflammatory cytokine overexpression via macrophage α7 nAChR activation and subsequent IL-10 ex... | |||
T14333 | Asoxime dichloride | Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate,Asoxime (dichloride),HI-6 | AChR |
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antig... | |||
T28531 | Facinicline hydrochloride | RG3487 | 5-HT Receptor , AChR |
Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot... | |||
T28856 | SSR180711 hydrochloride | SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl | AChR |
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders. |